This guest post was written by Mark Wanner from The Jackson Laboratory. He has previously written a guest post for us in 2013 responding to an article in the New York Times. This article is adapted from his earlier post on the The Jackson Laboratory blog, Genetics and your health, here. This focuses on a recent Nature commentary by Steve Perrin, which has been misunderstood by many in the animal rights community. Mark also discusses ways of improving the accuracy of the mouse model.
In February 2013, I wrote a post about the use of mice in preclinical research. It was largely in response to a New York Times article about a scientific paper that impugned data obtained from mice used in trauma and sepsis research. The NYT article in turn implied that research using mouse models for human disease was pretty much useless, or misleading at best.